Biologic Therapies for Aging Discs Henderson NV

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Archie C Perry, MD
(701) 731-1616
2800 E Desert Inn Rd
Las Vegas, NV
Business
Desert Orthopaedic Center
Specialties
Orthopedics

Data Provided By:
Roger A Fontes
(702) 564-1234
1681 W Horizon Ridge Parkway
Henderson, NV
Specialty
Orthopedic Surgery

Data Provided By:
Darrell K Spilsbury, DDS
(702) 733-9823
731 Mall Ring Cir Ste 100
Henderson, NV
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Wilfred Krom, MD
(213) 749-4355
Henderson, NV
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of The Witwatersrand, Med Sch, Johannesburg, So Africa
Graduation Year: 1959

Data Provided By:
Frederick C Redfern, MD
(702) 456-2400
600 Whitney Ranch Dr Ste D22
Henderson, NV
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Nv Sch Of Med, Reno Nv 89557
Graduation Year: 1983

Data Provided By:
G. Michael Elkanich, M.D.
(702) 474-7200
2020 Palomino Lane
Las Vegas, NV
Business
Bone & Joint Specialists
Specialties
Orthopedics, Degenerative Spinal Conditions
Cervical, Thoracic, and Lumbar Fusion
Cervical, Thoracic, and Lumbar Diskectomy
Cervical, Thoracic, and Lumbar Decompression
Total Disk Replacement - Cervical & Lumbar
Endoscopic Spinal Fusion
M
Insurance
Medicare Accepted: Yes
Workmens Comp Accepted: Yes
Accepts Uninsured Patients: Yes
Emergency Care: Yes

Doctor Information
Primary Hospital: Valley Medical Center
Residency Training: Stanford University Hosptial & Clinics
Medical School: University Of Arizona College of Medicine, 1997
Additional Information
Member Organizations: North American Spine Society
American Academy of Orthopaedic Surgeons
American Medical Association
State Medical Society
State Orthopaedic Society

Awards: American Board of Orthopaedic Surgeons - Board Certified
Languages Spoken: English,Spanish,Chinese

Data Provided By:
Michael S Ravitch
(702) 564-1234
1681 W Horizon Ridge Pkwy
Henderson, NV
Specialty
Orthopedic Surgery

Data Provided By:
Bowen D Miles, DMD
(702) 565-4646
390 N Stephanie St Ste 104
Henderson, NV
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Joel David Stewart, MD
Henderson, NV
Specialties
Orthopedics
Gender
Male
Education
Medical School: Harvard Med Sch, Boston Ma 02115
Graduation Year: 1993

Data Provided By:
Michael Miao, MD
Henderson, NV
Specialty
Orthopaedic Sugeon

Data Provided By:
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Biologic Therapies for Aging Discs

The lines and wrinkles on our faces aren't the only signs of the inevitable aging process. Progressive degenerative changes have also been documented in the spine. One of the areas of great interest is the intervertebral disc . New biologic therapies for aging discs are the subject of this review article on the topic.

There are 33 vertebrae or spinal bones. Between each vertebra is a disc made of tough cartilage with a fluid center. These discs provide the cushion that allows your backbone to bend and twist. Discs also act like shock absorbers as we walk, run, and jump. Each vertebral segment consists of bone next to bone with a cartilage cushion between. They are tied together with connective tissue, ligaments, and tendons.

Degenerative disc disease is an example of something that affects most people as they get older. Everyone is going to have a certain amount of damage to the spine. This occurs throughout a lifetime. The discs can flatten, and protrude from between the bones. In time, most people will have small tears in the outer layers of these discs.

Finding ways to repair damage to the discs is the focus of many research studies. One of the most recent directions in research has been the use of biologic therapies to restore the disc. Examples of these treatment approaches include disc cell reimplantation, stem cell implantation, disc denervation, injection of therapeutic proteins, and gene therapy.

What are these therapies and how do they work? Biologic therapies of this type are meant to help at the cellular level. Scientists have shown that inside the cells of the disc there is a limited amount of blood flow. As a result, there are waste products building up. The cell becomes very acidic and that is a harsh environment that doesn't support cell health very well.

As we age, there are fewer new cells to replace the old. Fluid leaks out of the discs that never gets replaced. We start to lose the strength of the discs needed to cushion and support the spine. A loss of disc height can lead to disc space collapse.

That's what's happening on the inside at the cellular level. On the outside, the affected individual may not feel anything until the degenerative process has gone on quite a while. Eventually, back pain, loss of motion, and loss of function get our attention. By then, there may not be much that can be done to save the disc. Right now, surgery to remove the disc is often the only option.

That could change if any of these biologic therapies can be perfected. Right now they are still in the experimental stages. Most of the studies have been done on animals but a few human trials have been conducted.

For example, disc tissue reimplantation is a process in which a few healthy cells are removed from an intact disc. They are taken to a lab where they can be multiplied and then reinjected into the diseased disc. The hope is that the new, healthy cells will replace the damaged cells and restore the strength of t...

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