Biologic Therapies for Aging Discs Prineville OR

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Scot E Burgess, DMD
(541) 923-7432
PO Box 697 710 SW Highland Ave
Redmond, OR
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Richard Henry Bolt, MD
(541) 923-4382
3310 NW Tetherow Bridge Loop
Redmond, OR
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Il Coll Of Med, Chicago Il 60680
Graduation Year: 1970
Hospital
Hospital: Memorial Hospital At Oconomowo, Oconomowoc, Wi; Waukesha Memorial Hospital, Waukesha, Wi
Group Practice: Orthopaedic Assoc-Waukesha

Data Provided By:
James Roy Karmy, MD
(541) 923-0728
333 NW Larch Ave
Redmond, OR
Specialties
Orthopedics
Gender
Male
Education
Medical School: Loma Linda Univ Sch Of Med, Loma Linda Ca 92350
Graduation Year: 1973
Hospital
Hospital: Mountain View Hospital Dist, Madras, Or; Central Oregon District Hosp, Redmond, Or
Group Practice: Redmond Orthopedic Clinic

Data Provided By:
Seth Leopold Goldsmith
(503) 786-8435
10100 Se Sunnyside Rd
Clackamas, OR
Specialty
Adult Reconstructive Orthopaedic Surgery

Data Provided By:
Brett Alan Lantz, MD
(541) 485-8111
1200 Hilyard S-600
Eugene, OR
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Ok Coll Of Med, Oklahoma City Ok 73190
Graduation Year: 1985

Data Provided By:
Kathleen R Moore, MD
(541) 388-2333
2300 SW Glacier Pl
Redmond, OR
Specialties
Orthopedics
Gender
Female
Education
Medical School: Or Hlth Sci Univ Sch Of Med, Portland Or 97201
Graduation Year: 1989

Data Provided By:
Dr.Brett Gingold
(541) 388-2333
1315 Northwest 4th Street
Redmond, OR
Gender
M
Education
Medical School: Univ Of Vt Coll Of Med
Year of Graduation: 1997
Speciality
Orthopedic Surgeon
General Information
Accepting New Patients: Yes
RateMD Rating
5.0, out of 5 based on 3, reviews.

Data Provided By:
Thad C Stanford
(503) 371-3129
3360 Croisan Creek Rd S
Salem, OR
Specialty
Orthopedic Surgery

Data Provided By:
Mark A Foreman, MD
(541) 244-2044
625 Ramsey Ave Ste A
Grants Pass, OR
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Tx Med Sch At San Antonio, San Antonio Tx 78284
Graduation Year: 1993

Data Provided By:
James Robert Loch
(503) 203-2096
9427 Sw Barnes Rd
Portland, OR
Specialty
Orthopedic Surgery

Data Provided By:
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Biologic Therapies for Aging Discs

The lines and wrinkles on our faces aren't the only signs of the inevitable aging process. Progressive degenerative changes have also been documented in the spine. One of the areas of great interest is the intervertebral disc . New biologic therapies for aging discs are the subject of this review article on the topic.

There are 33 vertebrae or spinal bones. Between each vertebra is a disc made of tough cartilage with a fluid center. These discs provide the cushion that allows your backbone to bend and twist. Discs also act like shock absorbers as we walk, run, and jump. Each vertebral segment consists of bone next to bone with a cartilage cushion between. They are tied together with connective tissue, ligaments, and tendons.

Degenerative disc disease is an example of something that affects most people as they get older. Everyone is going to have a certain amount of damage to the spine. This occurs throughout a lifetime. The discs can flatten, and protrude from between the bones. In time, most people will have small tears in the outer layers of these discs.

Finding ways to repair damage to the discs is the focus of many research studies. One of the most recent directions in research has been the use of biologic therapies to restore the disc. Examples of these treatment approaches include disc cell reimplantation, stem cell implantation, disc denervation, injection of therapeutic proteins, and gene therapy.

What are these therapies and how do they work? Biologic therapies of this type are meant to help at the cellular level. Scientists have shown that inside the cells of the disc there is a limited amount of blood flow. As a result, there are waste products building up. The cell becomes very acidic and that is a harsh environment that doesn't support cell health very well.

As we age, there are fewer new cells to replace the old. Fluid leaks out of the discs that never gets replaced. We start to lose the strength of the discs needed to cushion and support the spine. A loss of disc height can lead to disc space collapse.

That's what's happening on the inside at the cellular level. On the outside, the affected individual may not feel anything until the degenerative process has gone on quite a while. Eventually, back pain, loss of motion, and loss of function get our attention. By then, there may not be much that can be done to save the disc. Right now, surgery to remove the disc is often the only option.

That could change if any of these biologic therapies can be perfected. Right now they are still in the experimental stages. Most of the studies have been done on animals but a few human trials have been conducted.

For example, disc tissue reimplantation is a process in which a few healthy cells are removed from an intact disc. They are taken to a lab where they can be multiplied and then reinjected into the diseased disc. The hope is that the new, healthy cells will replace the damaged cells and restore the strength of t...

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