Biologic Therapies for Aging Discs Waupaca WI

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James Henry De Weerd, MD
(715) 345-5100
190 Grand Seasons Dr
Waupaca, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1972

Data Provided By:
David Michael Henneghan, MD
(715) 342-7950
190 Grand Seasons Dr
Waupaca, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Mi State Univ Coll Of Human Med, East Lansing Mi 48824
Graduation Year: 1984
Hospital
Hospital: St Michaels Hospital, Stevens Point, Wi
Group Practice: Ministry Health Care At Rice Medical Center; Rice Medical Center Ministry Health Care

Data Provided By:
Sean P Keane MD
(414) 277-1155
2015 E Newport Ave
Milwaukee, WI
Specialties
Orthopedics

Data Provided By:
Mark Ahrens Bauer, MD
(414) 529-2100
11035 W Forest Home Ave
Hales Corners, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Med Coll Of Wi, Milwaukee Wi 53226
Graduation Year: 1973

Data Provided By:
George G Hartl, DDS
(262) 334-2361
1305 Chestnut St
West Bend, WI
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Kim Harold Lulloff, MD
Waupaca, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Med Coll Of Wi, Milwaukee Wi 53226
Graduation Year: 1960

Data Provided By:
Dr. Rodney Lefler
Neuroscience Group of NE Wisconsin
920-725-9373 or toll free 800-201-1194
1305 W. American Drive
Neenah, WI
Specialty
Chiropractor
Conditions
Cervical spine disorders,Degenerative disc disease,Degenerative spinal conditions,Herniated disc / bulging disc,Lumbar spine disorders,Muscle pain / muscle strain,Neck pain,Sciatica / radiculopathy,Scoliosis and deformity,Spinal stenosis,Spondylolisthesis,Sports injuries,Thoracic spine disorders,Whiplash
Treatments
Exercise,McKenzie Method,Musculoskeletal manipulation,Physical therapy,Rehabilitation,Sports medicine,Strength and Conditioning
Proffesional Affiliation
Wisconsin Chiropractic Association,National Strength and Conditioning Association

Charles P Nolte
(608) 791-9876
800 West Ave S
La Crosse, WI
Specialty
Orthopedic Surgery

Data Provided By:
William Keith Kahle, MD
1313 Fish Hatchery Rd
Madison, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1975

Data Provided By:
Robert Patrick Limoni, MD
(920) 288-8200
2845 Greenbrier Rd Ste 210
Green Bay, WI
Specialties
Orthopedics
Gender
Male
Education
Medical School: Med Coll Of Wi, Milwaukee Wi 53226
Graduation Year: 1996

Data Provided By:
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Biologic Therapies for Aging Discs

The lines and wrinkles on our faces aren't the only signs of the inevitable aging process. Progressive degenerative changes have also been documented in the spine. One of the areas of great interest is the intervertebral disc . New biologic therapies for aging discs are the subject of this review article on the topic.

There are 33 vertebrae or spinal bones. Between each vertebra is a disc made of tough cartilage with a fluid center. These discs provide the cushion that allows your backbone to bend and twist. Discs also act like shock absorbers as we walk, run, and jump. Each vertebral segment consists of bone next to bone with a cartilage cushion between. They are tied together with connective tissue, ligaments, and tendons.

Degenerative disc disease is an example of something that affects most people as they get older. Everyone is going to have a certain amount of damage to the spine. This occurs throughout a lifetime. The discs can flatten, and protrude from between the bones. In time, most people will have small tears in the outer layers of these discs.

Finding ways to repair damage to the discs is the focus of many research studies. One of the most recent directions in research has been the use of biologic therapies to restore the disc. Examples of these treatment approaches include disc cell reimplantation, stem cell implantation, disc denervation, injection of therapeutic proteins, and gene therapy.

What are these therapies and how do they work? Biologic therapies of this type are meant to help at the cellular level. Scientists have shown that inside the cells of the disc there is a limited amount of blood flow. As a result, there are waste products building up. The cell becomes very acidic and that is a harsh environment that doesn't support cell health very well.

As we age, there are fewer new cells to replace the old. Fluid leaks out of the discs that never gets replaced. We start to lose the strength of the discs needed to cushion and support the spine. A loss of disc height can lead to disc space collapse.

That's what's happening on the inside at the cellular level. On the outside, the affected individual may not feel anything until the degenerative process has gone on quite a while. Eventually, back pain, loss of motion, and loss of function get our attention. By then, there may not be much that can be done to save the disc. Right now, surgery to remove the disc is often the only option.

That could change if any of these biologic therapies can be perfected. Right now they are still in the experimental stages. Most of the studies have been done on animals but a few human trials have been conducted.

For example, disc tissue reimplantation is a process in which a few healthy cells are removed from an intact disc. They are taken to a lab where they can be multiplied and then reinjected into the diseased disc. The hope is that the new, healthy cells will replace the damaged cells and restore the strength of t...

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