Cell Therapy for Cartilage Repair Booneville MS

Looking for information on Cell Therapy for Cartilage Repair in Booneville? We have compiled a list of businesses and services around Booneville that should help you with your search. We hope this page helps you find information on Cell Therapy for Cartilage Repair in Booneville.

John Eric Foropoulos, MD
(662) 286-6369
703 Alcorn Dr Doctors Office Plaza Ste 109
Corinth, MS
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Tn, Memphis, Coll Of Med, Memphis Tn 38163
Graduation Year: 1989
Hospital
Hospital: Magnolia Regional Health Cente, Corinth, Ms
Group Practice: Magnolia Orthopaedic & Sports

Data Provided By:
Robert H Perry, DDS
(662) 287-6151
1017 Foote St
Corinth, MS
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Edward Lee Engel, DMD
(662) 378-8645
843 S Main St
Greenville, MS
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Karl Lee Bierdeman, DDS
(601) 981-3036
2680 River Ridge Dr
Jackson, MS
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Thomas Brandon Paynter
(228) 376-0428
301 Fisher St
Keesler Afb, MS
Specialty
Orthopedic Surgery

Data Provided By:
Randall Parks Frazier, MD
(662) 286-6369
703 Alcorn Dr Ste 109
Corinth, MS
Specialties
Orthopedics
Gender
Male
Education
Medical School: Vanderbilt Univ Sch Of Med, Nashville Tn 37232
Graduation Year: 1986
Hospital
Hospital: Magnolia Regional Health Cente, Corinth, Ms
Group Practice: Magnolia Orthopaedic & Sports

Data Provided By:
Robert P Lorentz, DDS
(662) 286-3891
1500 N Harper Road Ext Ste 5
Corinth, MS
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
John Patrick Peden, MD
(601) 354-4499
1325 E Fortification St
Jackson, MS
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 2000

Data Provided By:
Scott Lewis Silver, MD
(601) 442-3345
140 Jefferson Davis Blvd Ste A
Natchez, MS
Specialties
Orthopedics
Gender
Male
Education
Medical School: Temple Univ Sch Of Med, Philadelphia Pa 19140
Graduation Year: 1971

Data Provided By:
Gregg Alan Gober, MD
(662) 332-8700
1693 S Colorado St
Greenville, MS
Specialties
Orthopedics
Gender
Male
Education
Medical School: Univ Of Ar Coll Of Med, Little Rock Ar 72205
Graduation Year: 1989
Hospital
Hospital: Delta Med Ctr, Greenville, Ms
Group Practice: Mid South Orthopaedics

Data Provided By:
Data Provided By:

Cell Therapy for Cartilage Repair: A Review and Update

Research into repair techniques for damage to knee cartilage is moving right along. Surgeons in Europe and Australia are ahead of American surgeons as they have moved from first-generation cartilage repair through second generation methods to the more current third-generation approaches.

Only one type of third-generation cell therapy for cartilage repair is available in the United States: the matrix-induced autologous chondrocyte implantation or MACI. MACI is the subject of this review article. Although it is being used by U.S. surgeons, the U.S. Food and Drug Administration (FDA) has not yet approved this type of cell carrier yet.

But let's step back a minute and get some background information that will help you understand what's going on. The basic problem is one of damage to the articular (joint surface) cartilage of the knee. The hole or defect can be small but deep (all the way down to the bone). Sometimes, the defect is large (wide and deep).

The affected person experiences knee pain and joint swelling, locking, stiffness, and clicking. The symptoms can be bad enough to interfere with daily activities at home and work and create quite a bit of disability. Sports participation can be out of the question.

Because so many athletes are affected and given the fact that knee joint (articular) cartilage doesn't repair itself, researchers started looking for ways to treat cartilage injuries of this type. They tried scraping the area and smoothing it down, a procedure called debridement. They tried drilling tiny holes into the bone marrow to stimulate bone healing. That's called microfracture. And they tried taking healthy cartilage from one part of the knee and transferring it to the lesion to fill in the hole.

All of these treatment methods had problems. There wasn't one approach that could work well for all different types and sizes of cartilage defects. That's when cell therapy was developed. Healthy cartilage cells (chondrocytes) were harvested from the knee but instead of using them directly in the damaged area, they were transferred to a lab. In the lab, the cells were used to grow more cells. When there were enough cells to fill in the hole, they were reimplanted into the patient and covered with a patch made of periosteal (bone) cells.

That procedure was called autologous chondrocyte implantation (ACI). It was the first cell therapy devised for the problem of full-thickness (down to the bone) cartilage injuries. That's why it's considered a first-generation approach to cell therapy cartilage repair. But again there were problems. The procedure is invasive and requires a two-step (staged) surgical procedure. That means at least two surgeries with all of the possible costs and risks that go with staged procedures.

The next batch of autologous chondrocyte implants were improved and formed the second-generation techniques. Instead of covering the patched up hole with periosteum (bone cells), they t...

Click here to read the rest of this article from eOrthopod.com