Cell Therapy for Cartilage Repair Duluth GA

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Lawrence A. Bircoll, M.D.
(770) 491-3003
2680 Lawrenceville Highway
Decatur, GA
Business
Resurgens Orthopedics
Specialties
Orthopedics
Insurance
Insurance Plans Accepted: We accept most insurance plans

Doctor Information
Primary Hospital: Dekalb Medical Center
Residency Training: Henry Ford Hospital, Detroit, Michigan
Medical School: University of Michigan School of Medicine,
Additional Information
Member Organizations: American Academy of Orthopaedics Medical Association of Georgia Atlanta Orthoapedic Society
Languages Spoken: English

Data Provided By:
F. daniel Koch, M.D.
(770) 491-3003
2680 Lawrenceville Highway
Decatur, GA
Business
Resurgens Orthopedics
Specialties
Orthopedics, General Orthopaedics, Adult Spine Surgery
Insurance
Insurance Plans Accepted: Accept most insurance plans

Doctor Information
Primary Hospital: Dekalb Medical Center
Residency Training: University of Louisville
Medical School: Duke University,
Additional Information
Member Organizations: Fellow, American Academy of Orthopaedic Surgeons
Languages Spoken: English

Data Provided By:
George Thurman Mitchell, DDS
(770) 923-8333
3709 Buford Hwy
Duluth, GA
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Timothy Scott Maughon, MD
(770) 813-8888
3855 Pleasant Hill Rd Ste 470
Duluth, GA
Specialties
Orthopedics
Gender
Male
Education
Medical School: Med Coll Of Ga Sch Of Med, Augusta Ga 30912
Graduation Year: 1986
Hospital
Hospital: Gwinnett Med Ctr, Lawrenceville, Ga
Group Practice: Sports Medicine & Orthopedic

Data Provided By:
Paul L Ouellette, DDS
(770) 622-9291
3530 Mall Blvd Ste B
Duluth, GA
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Sami O. Khan, M.D.
(770) 491-3003
2680 Lawrencevill Highway
Decatur, GA
Business
Resrugens Orthopaedics
Specialties
Orthopedics, Arthroscopic and Reconstructive Surgery of the Shoulder, Elbow and Knee, Sports Medicine, General Orthopaedics
Insurance
Insurance Plans Accepted: We accept most insurance plans

Doctor Information
Primary Hospital: Emory Eastside Hospital
Residency Training: New York University Hospital fo rJoint Disease
Medical School: Emory University School of Medicine,
Additional Information
Member Organizations: American Academy of Orthopaedic Surgeons, Arthroscopy Association of North America, American Orthopaedic Society of Sports Medicine
Awards: Associate Team Physician, New York Mets MLB 2003-2004 Team Physician, Mississippi Valley State Delta Devils 2006-2007 Associate Physician, Alvin Ailey Dance Theater New York, 2004 Author of multiple textbook chapters involving shoulder and elbow injuri
Languages Spoken: English,Spanish

Data Provided By:
Harold E Hickam, DDS
(478) 987-6522
PO Box 1592
Duluth, GA
Specialties
Orthodontics/Dentofacial Orthopedics

Data Provided By:
Robert David Rockfeld, MD
(770) 995-3300
3490 Pleasant Hill Rd
Duluth, GA
Specialties
Orthopedics
Gender
Male
Education
Medical School: Jefferson Med Coll-Thos Jefferson Univ, Philadelphia Pa 19107
Graduation Year: 1968

Data Provided By:
Jesse Edward Seidman, MD
(770) 889-0891
3540 Duluth Park Ln Ste 220
Duluth, GA
Specialties
Orthopedics
Gender
Male
Education
Medical School: Suny-Hlth Sci Ctr At Syracuse, Coll Of Med, Syracuse Ny 13210
Graduation Year: 1986

Data Provided By:
Mark Cullen, MD
Duluth, GA
Specialty
Orthopaedic Sugeon

Data Provided By:
Data Provided By:

Cell Therapy for Cartilage Repair: A Review and Update

Research into repair techniques for damage to knee cartilage is moving right along. Surgeons in Europe and Australia are ahead of American surgeons as they have moved from first-generation cartilage repair through second generation methods to the more current third-generation approaches.

Only one type of third-generation cell therapy for cartilage repair is available in the United States: the matrix-induced autologous chondrocyte implantation or MACI. MACI is the subject of this review article. Although it is being used by U.S. surgeons, the U.S. Food and Drug Administration (FDA) has not yet approved this type of cell carrier yet.

But let's step back a minute and get some background information that will help you understand what's going on. The basic problem is one of damage to the articular (joint surface) cartilage of the knee. The hole or defect can be small but deep (all the way down to the bone). Sometimes, the defect is large (wide and deep).

The affected person experiences knee pain and joint swelling, locking, stiffness, and clicking. The symptoms can be bad enough to interfere with daily activities at home and work and create quite a bit of disability. Sports participation can be out of the question.

Because so many athletes are affected and given the fact that knee joint (articular) cartilage doesn't repair itself, researchers started looking for ways to treat cartilage injuries of this type. They tried scraping the area and smoothing it down, a procedure called debridement. They tried drilling tiny holes into the bone marrow to stimulate bone healing. That's called microfracture. And they tried taking healthy cartilage from one part of the knee and transferring it to the lesion to fill in the hole.

All of these treatment methods had problems. There wasn't one approach that could work well for all different types and sizes of cartilage defects. That's when cell therapy was developed. Healthy cartilage cells (chondrocytes) were harvested from the knee but instead of using them directly in the damaged area, they were transferred to a lab. In the lab, the cells were used to grow more cells. When there were enough cells to fill in the hole, they were reimplanted into the patient and covered with a patch made of periosteal (bone) cells.

That procedure was called autologous chondrocyte implantation (ACI). It was the first cell therapy devised for the problem of full-thickness (down to the bone) cartilage injuries. That's why it's considered a first-generation approach to cell therapy cartilage repair. But again there were problems. The procedure is invasive and requires a two-step (staged) surgical procedure. That means at least two surgeries with all of the possible costs and risks that go with staged procedures.

The next batch of autologous chondrocyte implants were improved and formed the second-generation techniques. Instead of covering the patched up hole with periosteum (bone cells), they t...

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